diff --git a/lang/python/pillow/Makefile b/lang/python/pillow/Makefile
index c6b1faf0ee..d36f2bc2f9 100644
--- a/lang/python/pillow/Makefile
+++ b/lang/python/pillow/Makefile
@@ -7,13 +7,14 @@
 include $(TOPDIR)/rules.mk
 
 PKG_NAME:=pillow
-PKG_VERSION:=10.1.0
+PKG_VERSION:=12.1.1
 PKG_RELEASE:=1
 
 PYPI_NAME:=Pillow
-PKG_HASH:=e6bf8de6c36ed96c86ea3b6e1d5273c53f46ef518a062464cd7ef5dd2cf92e38
+PYPI_SOURCE_NAME:=pillow
+PKG_HASH:=9ad8fa5937ab05218e2b6a4cff30295ad35afd2f83ac592e68c0d871bb0fdbc4
 
-PKG_BUILD_DEPENDS:=python-setuptools-scm/host
+PKG_BUILD_DEPENDS:=python-setuptools/host python-pybind11/host
 
 PKG_MAINTAINER:=Alexandru Ardelean <ardeleanalex@gmail.com>
 PKG_LICENSE:=HPND
@@ -39,17 +40,15 @@ define Package/python3-pillow/description
 endef
 
 PYTHON3_PKG_BUILD_CONFIG_SETTINGS += \
-	--build-option=build_ext \
-	--build-option=--enable-zlib \
-	--build-option=--enable-jpeg \
-	--build-option=--enable-webp \
-	--build-option=--enable-webpmux \
-	--build-option=--enable-tiff \
-	--build-option=--enable-freetype \
-	--build-option=--disable-lcms \
-	--build-option=--disable-jpeg2000 \
-	--build-option=--disable-imagequant \
-	--build-option=--disable-platform-guessing
+	zlib=enable \
+	jpeg=enable \
+	webp=enable \
+	tiff=enable \
+	freetype=enable \
+	lcms=disable \
+	jpeg2000=disable \
+	imagequant=disable \
+	platform-guessing=disable
 
 $(eval $(call Py3Package,python3-pillow))
 $(eval $(call BuildPackage,python3-pillow))
diff --git a/lang/python/pillow/patches/001-remove-setuptools-version-limit.patch b/lang/python/pillow/patches/001-remove-setuptools-version-limit.patch
deleted file mode 100644
index e5ac168cbf..0000000000
--- a/lang/python/pillow/patches/001-remove-setuptools-version-limit.patch
+++ /dev/null
@@ -1,11 +0,0 @@
---- a/pyproject.toml
-+++ b/pyproject.toml
-@@ -1,7 +1,7 @@
- [build-system]
- build-backend = "backend"
- requires = [
--  "setuptools>=67.8",
-+  "setuptools",
- ]
- backend-path = [
-   "_custom_build",
diff --git a/lang/python/pillow/test.sh b/lang/python/pillow/test.sh
index 9bad292415..136f6e385b 100644
--- a/lang/python/pillow/test.sh
+++ b/lang/python/pillow/test.sh
@@ -4,13 +4,23 @@
 
 python3 - << EOF
 import sys
-from PIL import Image, ImageDraw
+from PIL import Image, ImageDraw, features
 
 if (Image.__version__ != "$2"):
     print("Wrong version: " + Image.__version__)
     sys.exit(1)
 
-from PIL import Image, ImageDraw
+# Check format/codec support
+for feature, name in [
+    ("webp",          "WebP"),
+    ("libjpeg_turbo", "JPEG"),
+    ("libtiff",       "TIFF"),
+    ("freetype2",     "FreeType"),
+]:
+    if not features.check(feature):
+        print(f"{name} support not available")
+        sys.exit(1)
+
 img = Image.new('RGB', (100, 30), color = (73, 109, 137))
 d = ImageDraw.Draw(img)
 d.text((10,10), "Hello World", fill=(255,255,0))